A Comparative Evaluation of Intravenous Analgesia, Thoracic Epidural Analgesia, and Erector Spinae Plane Block on Chronic Postoperative Pain Following Open Heart Surgery

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY

This prospective observational study aims to compare three routinely used postoperative analgesia techniques in patients undergoing open heart surgery: intravenous analgesia, thoracic epidural analgesia (TEA), and bilateral erector spinae plane block (ESPB). The primary objective is to evaluate the impact of these analgesia modalities on the development of chronic postoperative pain at 3 months. Secondary objectives include assessing postoperative acute pain scores, additional analgesic requirements, extubation time, mobilization time, intensive care unit stay, hospital stay, respiratory complications, and the relationship between acute and chronic pain. No intervention is assigned by protocol, and all analgesia methods are applied as part of routine clinical practice.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 85
Healthy Volunteers: f
View:

• Adults aged 18 to 85 years

• Classified as ASA physical status I-III

• Scheduled to undergo open heart surgery with median sternotomy

• BMI \< 35 kg/m²

• Able to understand and provide written informed consent

• Eligible to receive any of the routine analgesia methods (intravenous analgesia, thoracic epidural analgesia, or erector spinae plane block)

Locations
Other Locations
Turkey
Karadeniz Technical University Farabi Hospital
RECRUITING
Trabzon
Contact Information
Primary
Ali AKDOGAN, MD
draliakdogan@yahoo.com
+905322605414
Time Frame
Start Date: 2025-02-15
Estimated Completion Date: 2026-04-20
Participants
Target number of participants: 90
Treatments
Intravenous Analgesia Group (IV)
Participants who receive routine postoperative intravenous analgesia (opioid and/or non-opioid medications) as determined by the clinical anesthesia team. No protocol-assigned intervention is applied; analgesia is selected based on routine clinical practice.
Thoracic Epidural Analgesia Group (TEA)
Participants who receive thoracic epidural analgesia via an epidural catheter placed preoperatively for postoperative pain control. TEA is administered according to institutional routine practice and is not assigned by the study protocol
Erector Spinae Plane Block Group (ESPB)
Participants who receive bilateral erector spinae plane block (ESPB) performed preoperatively for postoperative analgesia. This block is a routine clinical procedure and is not assigned or modified by the study protocol.
Related Therapeutic Areas
Sponsors
Leads: Karadeniz Technical University

This content was sourced from clinicaltrials.gov